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Tag filter: Route Scouting and Selection

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    Tags

    • Biocatalysis (6)
    • Catalysis (15)
    • CatSci Paper (14)
    • CatSci Patent (2)
    • Design of Experiments (2)
    • Experimental Design (2)
    • Green Chemistry (27)
    • Material Science (5)
    • OPR&D (2)
    • Post-approval Life Cycle Management (1)
    • Principal Component Analysis (3)
    • Process R&D (22)
    • QbD (1)
    • Route Scouting and Selection (2)
    • Scale-up (12)
    • Scavenging (2)
    • Solvents (4)

January, 2021

Route Redesign to Eliminate Use of PhOCN

The route supplied by the client involved the use of phenyl cyanate for functionalising a heterocyclic intermediate with a nitrile group. Its ongoing use would require cyanide monitoring, a dedicated waste stream treatment step, and there were concerns over the sourcing of material of appropriate quality over the long term.

December, 2020

Effective Route Scouting allows Pilot Plant Slot to be met

CatSci was tasked with performing route-scouting, route selection and early-phase process development over a 6-month period to meet a pilot plant manufacturing slot.

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