Biocatalysis Archives - CatSci

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2022

Development of a Process to a 4-Arylated 2-Methylisoquinolin-1(2H)-one for the Treatment of Solid Tumors: Lessons in Ortho-Bromination, Selective Solubility, Pd Deactivation, and Form Control

Org. Process Res. Dev. 2022, 26, 5, 1458–1469

By: Antonio M. Ruda, Nadia Fleary-Roberts, Jonathan D. Moseley and Siân M. Forsyth et al.

2022

Application of the Polonovski Reaction: Scale-up of an Efficient and Environmentally Benign Opioid Demethylation

Org. Process Res. Dev. 2022

By: Antonio M. Ruda, Sofia Papadouli, Vargini Thangavadivale, and Jonathan D. Moseley et al.

2020

Ketone Reductase Biocatalysis in the Synthesis of Chiral Intermediates Toward Generic Active Pharmaceutical Ingredients

Org. Process Res. Dev. 2020

By: Jo Sampson, Dan Smith, Siân Forsyth et al.

2020

Application of bio-based solvents for biocatalysed synthesis of amides with Pseudomonas stutzeri lipase (PSL)

Pure and Applied Chemistry, 2019

By: Jonathan Moseley et al.

October, 2018

Opinion Piece – Why Biocatalysis?

Why Biocatalysis?

By: Andy Wells

2016

Process for the preparation of a stereospecific form of flurbiprofen, or a pharmaceutically acceptable salt

WO 2016/110708

By: CatSci et al.