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Papers

Read the team’s scientific Papers.

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Analytical Chemistry Analytical Science Artificial Intelligence (AI) Biocatalysis Catalysis CatSci Paper CatSci Patent Chemical Development Complex Synthetic Medicines Design of Experiments Digital Drug Development Experimental Design Green Chemistry Industry insights Innovation Machine Learning (ML) Material Science Medium Throughput Experimentation Oligonucleotides Peptides Principal Component Analysis Process R&D PROTACs QbD Route Scouting and Selection Scale-up Scavenging Solvents Sustainability Technology transfer Work-up
Highly diastereoselective radical cyclisations of chiral sulfinimines

Chem. Commun., 2013, 49, 9395-9397

2013 By Elise Rochette, et al.
Selective Au–C Cleavage in (C∧N∧C)Au(III) Aryl and Alkyl Pincer Complexes

Organometallics 2012, 31, 17, 5998–6000

2012 By Dan A. Smith, et al.
Measuring the Unmeasurable

Chemistry and Industry 2012, 76 (6), 16-17

2012 By CatSci team, et al.
A Thermally Stable Gold(III) Hydride: Synthesis, Reactivity, and Reductive Condensation as a...

Angew. Chem. Int. Ed. 2012, 51, 10643

2012 By Dan A. Smith, et al.
Switching Pathways: Room-Temperature Neutral Solvolysis and Substitution of Amides

Angew. Chem. Int. Ed. 2012, 51, 548-551

2012 By Marc HutchbySimon N. G. Tyler, et al.
C–H and C–O oxidative addition in reactions of aryl carboxylates with a PNP pincer-ligated R...

Chem. Commun., 2012, 48, 218-220

2012 By Dan A. Smith, et al.
A mild robust generic protocol for the Suzuki reaction using an air stable catalyst

Tetrahedron 2012, 68, 6010-6017

2012 By Simon N. G. Tyler, et al.
Going solo

Chemistry World 2012, 9 (9), 75

2012
Cyclometallated gold(iii) hydroxides as versatile synthons for Au–N, Au–C complexes and lumi...

Chem. Commun., 2012, 48, 7247-7249

2012 By Dan A. Smith, et al.
Discovery and Structure−Activity Relationship of 3-Aminopyrid-2-ones as Potent and Selective...

J. Med. Chem. 2011, 54, 7, 2341–2350

2012 By Guy Brenchley, et al.
Competition Studies of Oxidative Addition of Aryl Halides to the (PNP)Rh Fragment

Organometallics 2011, 30, 9, 2472–2482

2011 By Dan A. Smith, et al.
Early–late heterobimetallic Rh–Ti and Rh–Zr complexes via addition of early metal chlorides ...

Chem. Commun., 2011, 47, 10779-10781

2011 By Dan A. Smith, et al.
Exploiting Non-Innocent Ligands to Prepare Masked Palladium(0) Complexes

Angew. Chem. Int. Ed. 2010, 49, 7040

2010 By Dan A. Smith, et al.
An Improved Process for the Synthesis and Isolation of (S)-N-(1-Phenylethyl)hydroxylamine

Org. Process Res. Dev. 2009, 13, 1, 49–53

2009 By Simon N. G. Tyler, et al.
Room-Temperature Palladium-Catalyzed CH Activation: ortho-Carbonylation of Aniline Derivatives

Angew. Chem. Int. Ed. 2009, 48, 1830-1833

2009 By Marc HutchbySimon N. G. Tyler, et al.
From Cyclic Iminophosphoranes to π-Conjugated Materials

Angew. Chem. Int. Ed. 2009, 48, 9109

2009 By Dan A. Smith, et al.
Hindered Ureas as Masked Isocyanates: Facile Carbamoylation of Nucleophiles under Neutral Co...

Angew. Chem. Int. Ed. 2009, 48, 8721-8724

2009 By Marc HutchbySimon N. G. Tyler, et al.
A Truly Multifunctional Heterocycle: Iminophosphorane, N,P Chelate, and Dihydropyridine

Angew. Chem. Int. Ed. 2008, 47, 8674

2008 By Dan A. Smith, et al.
Validation and application of capillary electrophoresis for the analysis of lidocaine in a s...

Biomed. Chromatogr. 2007, 21, 775

2007 By Ross T. Burn, et al.
Synthesis of a Stable Pyridyl Boronate and Its Reaction with Aryl and Heteroaryl Halides

Heterocycles, 2006, 70, 509-517

2006 By Guy Brenchley, et al.
Comparison of non-invasive NIR and Raman spectrometries for determination of alcohol content...

Anal. Chim. Acta. 2005, 548, 148

2005 By Ross T. Burn, et al.
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What we do

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Who we are

CatSci Ltd are an award-winning innovation partner for medicines development who are committed to creating tailored solutions from candidate selection through product launch and beyond. We break down the silos in small molecules, TACS, glues and oligonucleotides CMC development to accelerate the delivery of life-changing medicines to patients in need. 

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