In this article, we will explore the importance of building translational assay cascades that prioritise human relevance and why it is crucial to bridge the gap between translational assays from lab to clinic
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Analytical Chemistry
Analytical Science
Artificial Intelligence (AI)
Beyond the Rule of 5
Biocatalysis
Bioscience
Catalysis
CatSci Paper
CatSci Patent
Chemical Development
Complex Synthetic Medicines
Design of Experiments
Digital
Drug Development
Experimental Design
Green Chemistry
Industry insights
Innovation
Machine Learning (ML)
Material Science
Medium Throughput Experimentation
Oligonucleotides
Peptides
Principal Component Analysis
Process R&D
PROTACs
QbD
Route Scouting and Selection
Scale-up
Scavenging
Solvents
Sustainability
Technology transfer
Work-up
Ryan Mordue explores how modern tools and modalities let scientists succeed with “beyond Rule of 5” molecules (peptides, oligos, TACs), showing why rigid Ro5 filters no longer define drug-like space and how CatSci’s new Bioscience platform delivers the data to de-risk these complex therapeutics.