Turning Peptide Discoveries into Scalable, Robust Therapies is a Complex Challenge
Pharmaceutical companies operate in high-stakes environments.
Typical peptide synthesis challenges we see:
- Quality & Consistency: Even minor variations in purity can derail synthesis, skew data, and disrupt development progress.
- Complex Chemistry & Expertise Gaps: Specialised modifications, challenging sequences, and limited in-house knowledge can derail timelines.
- Security & Transparency: Outsourcing risks IP, confidentiality, and communication breakdowns between customers and suppliers.
- Time Pressures & Investor Confidence: Pressure to deliver results swiftly and cost-effectively under investor scrutiny can impact quality.
“Time and again, I’ve seen projects struggle when they underestimate the complexity of peptide synthesis challenges.
It’s not just about making a sequence – it’s about ensuring total confidence in quality, strategy, communication, and partnership.”
Dr Jordan Fletcher
Technical Director at CatSci
Turning Complex Peptide Synthesis Challenges into Bespoke Opportunities
- Accelerating Timelines: Automated synthesis workflows and real-time monitoring reduce synthesis and purification time, helping to avoid costly delays.
- Expert Team for Complex Chemistry: Decades of peptide experience solving tough synthetic challenges, specialised modifications and demanding sequences tailored to your project’s needs.
- Advanced Purification with Reach Separations: Long-established and industry-leaders in separation science to ensure exacting purity and consistency of delivered peptide.
- Consistent Methodology & Comprehensive QC: Validated processes and cutting-edge analytics (LC/MS, HPLC) guarantee reliable, transparent outcomes.
- Agile Project Management: Proactive milestone tracking and open communication keep your R&D on schedule and within budget.
- Secure, UK-Based Production: No third-party outsourcing with strict NDAs – your IP stays protected and confidential, giving you peace of mind it’s safe in our UK-based lab.
Peptides at CatSci
Peptide Synthesis
CatSci’s new peptide synthesis capability is designed to streamline your drug discovery and development process, offering solutions for even the most complex peptides challenges.
Our state-of-the-art facility in BioCity, Nottingham, is home to a brand-new laboratory and a team of experts with decades of combined experience.
From discovery to multi-gram-scale production, we ensure innovative strategies to handle challenging sequences and custom modifications, and provide unparalleled support for your projects.
Speak to Us
Peptide Synthesis Capabilities
Tailored Synthesis and Modifications
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Range of Sequences: Linear peptides (2–45 amino acids), cyclic peptides (4–22 amino acids), peptoids, and more.
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Specialised Chemistries: Disulfide bridges, RCM, click reactions, stapled peptides, and branched architectures, etc.
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Conjugations & Labels: Lipopeptides, fluorescent tags, N-methylation, and other bespoke modifications.
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Flexible Scales: From microgram discovery phases up to multi-gram-scale manufacturing, within your required timelines.
- Bespoke Needs: For a full range of our capabilities, chat to us about your specific challenges.
Peptide Purification
Powered by Reach Separations
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Integrated Workflow: Crude peptide moves seamlessly between synthesis and purification laboratories within minutes, eliminating delays and exposure.
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Industry-Leading Techniques: Chiral & achiral HPLC, super-critical fluid chromatography (SFC), UPLC-MS and LC-MS for exacting purity.
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Flexible Scale: From mg to tens of grams; discovery batches through to larger scale, all under one roof.
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Impurity Isolation & Array Purification: Rapid impurity ID, fraction collection, and parallel purification to accelerate method optimisation.
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Our Peptides Experts
