Back to Smartpath
My account
1
2
3
4
5
6
7
Last Page
Question 1/10

Does the particle show an extreme
aspect ratio, or is it very small?
?N/A
Question 2/10

Is the powder flow poor?
?If the flow is good or acceptable, then answer “No”
.
Question 3/10

Is API bulk density low?
Question 4/10

Is the API a salt with an acidic counterion?
Question 5/10

If the API is a salt with an acidic counterion, is the pKa of the API less than 5?
Question 5/10

Is the number of salt forms identified
from the salt screen few in number?
?If response is Yes it means that many salts identified from screen or parent molecule have no acidic or basic groups
Question 6/10

Following detailed polymorph studies, have a large number of polymorphs solvates and hydrates been found?
Question 7/10

Does the computational informatics
assessment of the API suggest that
a more stable polymorph, hydrate or process
relevant solvate can exist?
?N/A
.
Question 8/10

Is the API hygroscopic?
?If your API picks up significant water, then it is hygroscopic. If “No”, it means that the selected version does not pick-up significant water.
Question 9/10

Is the melting point of the API low?
Question 10/10

Does the API require size reduction?
Question 11/11

If the API requires size reduction,
is there evidence of amorphisation?
?Amorphisation refers to a limited or amorphous content that is not measurable.
Sign in or create an account to access your risk assessment
Email Address
Password
Name
Surname
Company
Email
Password
Confirm Password

Logged in users only

Please login here to access the SmartPath assessment