• 6 Oct 2022
  • Antonio M. Ruda, Siân M. Forsyth

Development of a Process to a 4-Arylated 2-Methylisoquinolin-1(2H)-one for the Treatment of Solid Tumors: Lessons in Ortho-Bromination, Selective Solubility, Pd Deactivation, and Form Control

  • Catalysis
  • CatSci Paper
  • Green Chemistry
  • Process R&D
  • Scale-up
  • Papers

Resources & Insights

  • 5 Feb 2026
2nd Advances in Translational Drug Development 2026
  • Events
  • 4 Feb 2026
  • Loïc Roux
Make as Insight, Not Execution – Why “Make” Is the Most Misunderstood Step in DMTA
  • Design-Make-Test
  • DMTA
  • Thought Leaders
  • 22 Jan 2026
  • Loïc Roux
Designing Therapeutic Oligonucleotides – A Practical Framework from Biology to Sequence Selection
  • Design-Make-Test
  • DMTA
  • Oligonucleotides
  • Thought Leaders
  • 15 Jan 2026
  • Jordan Fletcher
Peptide Design in Contemporary DMTA Cycles: How DMTA Drives Translational Refinement
  • Design Make Test Analyse
  • DMTA
  • Peptides
  • Thought Leaders