Small Molecules
Integrated Small Molecule Expertise with a Green Chemistry Focus
We help our partners progress their small molecule assets with confidence. From retrosynthetic design and process optimisation to HPAPI containment and solid-state formulation, we deliver the scientific depth, infrastructure, and experience to take molecules smoothly from discovery to launch.
- Overview
- Integrated capability across the small molecule lifecycle
- Dedicated laboratories for small molecule development
- Why choose us
- In our own words
- FAQs
Small molecules remain the cornerstone of modern medicine, yet their development is not always straight forward.
At CatSci, we understand the significant development challenges that small molecules bring. Programmes often face the complexity of multiple potential routes with very different cost and sustainability profiles, while scale-up introduces risks around yield, impurities, and process robustness. For potent compounds, advanced containment is essential, and variability in solid-state can undermine both manufacturability and IP strategy
We go beyond developing chemistry. We design scalable, sustainable processes that deliver confidence, reduce risk, and accelerate your journey to the clinic.
Dedicated Laboratories for Small Molecule Development
Why Choose Us
- Trusted partner to 100+ biotechs and 7 of the global top 10 pharma companies
- Sustainability built into every process with auditable ESG metrics and My Green Lab certified labs
- Led by experts with decades of large pharma and biotech expertise
- Integrated labs and cross-functional teams that compress timelines and simplify workflows
- UK-based with transparent, scientist-to-scientist communication
Frequently Asked Questions
CatSci provides end-to-end small molecule development services covering discovery route scouting, process optimisation, and regulatory readiness. Our expertise spans retrosynthetic design, DoE-driven process chemistry, solid-state development, analytical validation, and scale-up from milligrams to kilograms.
Yes. CatSci is a SafeBridge®-audited partner with dedicated OEB-4 and OEB-5 containment suites for high-potency small molecule development. We safely handle compounds with OELs as low as 0.1 µg/m³, offering non-GMP production for tox and preclinical studies. Our HPAPI services ensure safe, compliant, and scalable development of potent drug substances.
Sustainability is built into every CatSci project. We apply green chemistry principles through catalytic efficiency, lifecycle PMI mapping, solvent recycling, and waste minimisation. Our My Green Lab-certified facilities ensure that each small molecule development programme meets both scientific and environmental performance standards.