Our Equipment
Our Equipment
Quick filter:
- Process R&D - standard
- Process R&D - OEB-5
- Process R&D - OEB-4
- Catalysis
- Analytical science
- Crystallisation, solid state and preformulation
- Oligonucleotides PR&D
- Oligonucleotides analytical
- Prep chromatography
Process R&D – Standard
250 mL-5L jacketed vessels
Radleys
250mL-5L filtration equipment
Used for large scale filtrations under positive or negative pressure, with heat jacket and overhead stirring
20L jacketed vessels
Labtex
Used to produce specimen scale-up batches up to around 1 kg
Used to produce specimen scale-up batches up to around 1 kg
Amigo reactor
Amigochem
Sampling and dilution of materials taken from the Integrity 10 reactor
Sampling and dilution of materials taken from the Integrity 10 reactor
Antistatic kit universal
Mettler Toledo
To assist with the weighing of static materials
To assist with the weighing of static materials
Centrifuge
Hettich
Chemicalize
ChemAxon
pKa, logP and 1H NMR predictions
pKa, logP and 1H NMR predictions
Cold plate
Maintaining a constant subambient temperature for chemistry performed in vials
Crystal 16
Technobis
Used to build solubility curves. 16 parallel screens in volumes 0.5 – 1.5 mL
Used to build solubility curves. 16 parallel screens in volumes 0.5 – 1.5 mL
Distimatic
Heidolph
Automated distillation unit
Automated distillation unit
DSC
Mettler Toledo
Thermal and thermodynamic stability of materials with autosampler
Thermal and thermodynamic stability of materials with autosampler
DynoChem
Mettler Toledo
Modelling software to enhance process understanding and develop scalable, robust unit operations quickly with reduced experimentation
Modelling software to enhance process understanding and develop scalable, robust unit operations quickly with reduced experimentation
EasySampler
Mettler-Toledo
Automated sampling and reaction profile monitoring, including air sensitive reactions.
Automated sampling and reaction profile monitoring, including air sensitive reactions.
ELN
Revvity Signals
Electronic lab notebook
Electronic lab notebook
EquaVAP Evaporator
EquaVAP
Used to evaporate solvent from vials in plates
Used to evaporate solvent from vials in plates
Heidolph Distimatic
Heidolph
Automated distillation & concentration of solvents, from 500 mL to > 20 L. Fully automated system, used mostly for large-scale processes
Automated distillation & concentration of solvents, from 500 mL to > 20 L. Fully automated system, used mostly for large-scale processes
Hot stage microscope
Zeiss
High resolution assessment of crystallinity, particle shape and size
High resolution assessment of crystallinity, particle shape and size
Huber Ministat 230
Huber
Used for heating and cooling reactors between 250 mL and 2 L from -40 °C to +200 °C
Used for heating and cooling reactors between 250 mL and 2 L from -40 °C to +200 °C
Huber Unistat 360
Huber
Used for heating and cooling reactors between 2 and 20 L from -75 °C to +200 °C
Used for heating and cooling reactors between 2 and 20 L from -75 °C to +200 °C
Huber Unistat 430
Huber
Used for heating and cooling reactors between 5 and 20 L from -40 °C to +250 °C
Used for heating and cooling reactors between 5 and 20 L from -40 °C to +250 °C
Integrity 10
Allows 10 tube-scale reactions to be performed in parallel with independent control of stirirng and heating
Isolera
Biotage
Automated flash system
Automated flash system
JMP 12
JMP
Statistical data analysis software
Statistical data analysis software
Karl Fischer coulometry
Metrohm
Detection of water content of samples
Detection of water content of samples
Labgear
Lab automation software
Melting point apparatus
Establishing the melting point of solids
MestreNova
Mestrelab
A suite of software to process analytical chemistry data
A suite of software to process analytical chemistry data
Microscope Axioscope 5
Zeiss
High resolution assessment of crystallinity, particle shape and size
High resolution assessment of crystallinity, particle shape and size
Mya 4 Reaction Station
Radleys
A 4-zone reaction station offering safe and precise heating, active cooling, software control and data-logging for 24/7 unattended chemistry.
A 4-zone reaction station offering safe and precise heating, active cooling, software control and data-logging for 24/7 unattended chemistry.
pH meter
Hanna
Polar Bear Plus
Cambridge Reactor Design
A heating and cooling plate that stirs and heats and cools from -40 °C to 150 °C.
A heating and cooling plate that stirs and heats and cools from -40 °C to 150 °C.
RX10 units
Mettler Toledo
RX-10 chemical reactor control system that automates jacketed laboratory reactors to ensure excellent reaction control and data-rich experimentation
RX-10 chemical reactor control system that automates jacketed laboratory reactors to ensure excellent reaction control and data-rich experimentation
SP-50 dosing unit
Mettler Toledo
Adding solutions to a vessel with feedback control to other peripherals
Adding solutions to a vessel with feedback control to other peripherals
Seven Excellence pH meter
Mettler Toledo
A multi-channel benchtop pH meter for precise measurements of pH, conductivity, dissolved oxygen, and ion concentration
A multi-channel benchtop pH meter for precise measurements of pH, conductivity, dissolved oxygen, and ion concentration
TGA
Mettler Toledo
Measuring levels of loosely bound solvent
Measuring levels of loosely bound solvent
TSu
HEL
Fast screening of thermal and pressure hazards
Fast screening of thermal and pressure hazards
VacMaster filtration unit
Biotage
Assessment of the filtration performance of parallel samples.
Assessment of the filtration performance of parallel samples.
Vapourtec R series
Vapourtec
Flow reactor, pump, UV-150 photoreactor and autosampler
Flow reactor, pump, UV-150 photoreactor and autosampler
Zotero
Zotero
Reference management system
Reference management system
Process R&D – OEB-5
EasyMax
Mettler Toledo
A 2-zone reaction station offering safe and precise heating, active cooling, software control and remote data-logging for 24/7 unattended chemistry.
A 2-zone reaction station offering safe and precise heating, active cooling, software control and remote data-logging for 24/7 unattended chemistry.
Greenhouse evaporator
Radleys
Low footprint concentration of high hazard solutions within an isolator environment
Low footprint concentration of high hazard solutions within an isolator environment
Isolator
CTS
Handling of compounds with OEL’s less than 0.03 µg/m3.
Handling of compounds with OEL’s less than 0.03 µg/m3.
VChamber
MeltPrep
Low footprint drying of high hazard solids within an isolator environment
Low footprint drying of high hazard solids within an isolator environment
Process R&D – OEB-4
Agilent 1100 x 2
Agilent
Walk up LC-MS, coupled to ZQ Mass Spec
Walk up LC-MS, coupled to ZQ Mass Spec
Controlled Substances Box
Used for keeping highly potent, pharmacologically active controlled substances. Keyholders strictly controlled & registered with Home Office; contents routinely audited to ensure compliance
EasyMax 102
Mettler Toledo
Enables the development of small scale reactions up to 100mL and with heating and cooling between -40 °C and +180 °C. Allows for integration of process analytical technology (PAT) or calorimetric information which enhances understanding of the progress of the reaction.
Enables the development of small scale reactions up to 100mL and with heating and cooling between -40 °C and +180 °C. Allows for integration of process analytical technology (PAT) or calorimetric information which enhances understanding of the progress of the reaction.
EasyMax 102 (including Optimax HFCal)
Mettler-Toledo
Enables the development of small scale reactions up to 100mL and with heating and cooling between -40 °C and +180 °C. Allows for integration of process analytical technology (PAT) or calorimetric information which enhances understanding of the progress of the reaction, potential risks and by-products, and is connected to a gas flow meter
Enables the development of small scale reactions up to 100mL and with heating and cooling between -40 °C and +180 °C. Allows for integration of process analytical technology (PAT) or calorimetric information which enhances understanding of the progress of the reaction, potential risks and by-products, and is connected to a gas flow meter
ECB Box
Mettler-Toledo
Connects EasyMax to 3rd party sensors
Connects EasyMax to 3rd party sensors
Filter dryer
Powder Systems
Isolation of highly potent materials
Isolation of highly potent materials
Huber CC-505
Huber
Used for heating and cooling reactors between 2 and 20 L from -75 °C to +200 °C
Used for heating and cooling reactors between 2 and 20 L from -75 °C to +200 °C
Huber Minichiller 600
Huber
Used for cooling and heating condensers at lab scale reactions (-20 °C to +40 °C). Part of our green chemistry initiative, reducing waste water (estimated to save at least 100 L per hour for each system) as coolant is recirculated
Used for cooling and heating condensers at lab scale reactions (-20 °C to +40 °C). Part of our green chemistry initiative, reducing waste water (estimated to save at least 100 L per hour for each system) as coolant is recirculated
Huber Ministat 230
Huber
Used for heating and cooling reactors between 250 mL and 2 L from -40 °C to +200 °C
Used for heating and cooling reactors between 250 mL and 2 L from -40 °C to +200 °C
Hydrogen generator
H-Genie
Supply of up to 100 bar pressure of hydrogen
Supply of up to 100 bar pressure of hydrogen
Isolator
CTS
Containment of highly potent materials
Containment of highly potent materials
Mya 4 Reaction Station
Radley
A 4-zone reaction station offering safe and precise heating, active cooling, software control and data-logging for 24/7 unattended chemistry
A 4-zone reaction station offering safe and precise heating, active cooling, software control and data-logging for 24/7 unattended chemistry
Nutsche filter dryer
Bachiller
Enables in situe drying of filtered material, reducing the handling steps in a potent environment. Agitation also allows for in-situ slurry washing of the filter cake, allowing for better reporoduction of certain manufacturing scale capabilities
Enables in situe drying of filtered material, reducing the handling steps in a potent environment. Agitation also allows for in-situ slurry washing of the filter cake, allowing for better reporoduction of certain manufacturing scale capabilities
Radley Reactor-Ready
Radley
Universal reactor work station with a range of easily interchangeable vessels from 250 mL to 5 L which can be configured to suit the chemistry and scale needed for each project
Universal reactor work station with a range of easily interchangeable vessels from 250 mL to 5 L which can be configured to suit the chemistry and scale needed for each project
Selekt and ELSD
Biotage
Automated flash system. ELSD allows the detection of analytes without a chromophore.
Automated flash system. ELSD allows the detection of analytes without a chromophore.
Tsu
H.E.L group
Used to screen different pressures and temperatures of a sample on the same platform
Used to screen different pressures and temperatures of a sample on the same platform
Catalysis
1L Buchi autoclave
Buchi
Allows for pressurised reactions up to 1L at 10 bar
Allows for pressurised reactions up to 1L at 10 bar
Biotage Endeavour
Biotage
Used for parallel, multi-reactor optimisation of pressurised reactions (8 x 1-4 mL tubes, up to 30 bar pressure and 200°C)
Used for parallel, multi-reactor optimisation of pressurised reactions (8 x 1-4 mL tubes, up to 30 bar pressure and 200°C)
Cat 7
HEL
7 position reactor for manual catalyst screening
7 position reactor for manual catalyst screening
Cat 96
HEL
96 position reactor for manual catalyst screening
96 position reactor for manual catalyst screening
Genevac EZ-2
Biopharma Group
Centrifugal solvent evaporator system
Centrifugal solvent evaporator system
Glove box
Mbraun
10 m3 Glovebox maintained at < 10 ppm O2, used for catalyst screening and sensitive reactions. Equipped with twin purifier system and 30 gloves
10 m3 Glovebox maintained at < 10 ppm O2, used for catalyst screening and sensitive reactions. Equipped with twin purifier system and 30 gloves
HEL Cat-96
H.E.L group
Used for high throughput catalyst screening in 96 well plates (96 x 200-1000 uL vials, up to 34 bar and 200 °C). Also available is the HEL Cat-7, used for parallel catalyst screening (7 x 3-20 mL tubes, up to 100 bar and 200 °C)
Used for high throughput catalyst screening in 96 well plates (96 x 200-1000 uL vials, up to 34 bar and 200 °C). Also available is the HEL Cat-7, used for parallel catalyst screening (7 x 3-20 mL tubes, up to 100 bar and 200 °C)
LED aquarium lamp and controller
Kessil
Photoredox reactions enabled by blue light
Photoredox reactions enabled by blue light
Man on the Moon
manonthemoontech.com
Monitoring hydrogen uptake in small scale hydrogenation reactions
Monitoring hydrogen uptake in small scale hydrogenation reactions
Miniclave Drive (300 mL)
Buchi
A multipurpose steel pressure reactor system designed for use with interchangeable steel pressure vessels.
A multipurpose steel pressure reactor system designed for use with interchangeable steel pressure vessels.
Parr hydrogenator
Parr Instrument Company
Used for high pressure reactions, handling volumes up to 600 mL
Used for high pressure reactions, handling volumes up to 600 mL
Pressflow controller
Buchi
System used to quantify the delivery of gasses
System used to quantify the delivery of gasses
Tumble stirrer
Agitation of biotransformations
Analytical Science
Agilent 1100/1200 HPLC x 4
Agilent
Used for process development. 1 x equipped with quaternary pump and Variable Wavelength Detector (VWD), used for chiral analysis
Used for process development. 1 x equipped with quaternary pump and Variable Wavelength Detector (VWD), used for chiral analysis
Agilent 1100/1200 HPLC-MS
Agilent
Equipped with ZQ mass spectrometer. Used for process development and optimisation
Equipped with ZQ mass spectrometer. Used for process development and optimisation
Agilent 1220 HPLC x 2
Agilent
Equipped with DAD/VWD. Used for general project support.
Equipped with DAD/VWD. Used for general project support.
Agilent 1220 HPLC-CAD
Agilent
DAD with Charged Aerosol Detector (CAD) for analysis of compounds with poor chromophores
DAD with Charged Aerosol Detector (CAD) for analysis of compounds with poor chromophores
Agilent 1260 HPLC x 2
Agilent
Equipped with DAD and Masshunter open-access interface, for general project support
Equipped with DAD and Masshunter open-access interface, for general project support
Agilent 1260 HPLC x 3
Agilent
Equipped with DAD/VWD. 1 x equipped with column switcher. Used for method development and project support
Equipped with DAD/VWD. 1 x equipped with column switcher. Used for method development and project support
Agilent 1260 HPLC-MS
Agilent
Equipped with 6150 mass spectrometer. Used for process development and optimisation
Equipped with 6150 mass spectrometer. Used for process development and optimisation
Agilent 1290 UPLC
Agilent
Used for method development and optimisation
Used for method development and optimisation
Agilent 1290 UPLC x 2
Agilent
1300 bar, 6 column switcher allows high throughput IPC analysis using generic methods across multiple projects. Masshunter open-access interface and automatic vial disposal provides simplified and optimised sample submission
1300 bar, 6 column switcher allows high throughput IPC analysis using generic methods across multiple projects. Masshunter open-access interface and automatic vial disposal provides simplified and optimised sample submission
Agilent 1290 UPLC-MS x 2
Agilent
1300 bar, 6 column switcher allows high throughput IPC analysis using generic methods across multiple projects. Masshunter open-access interface and automatic vial disposal provides simplified and optimised sample submission. iQ mass detector allows for process optimisation
1300 bar, 6 column switcher allows high throughput IPC analysis using generic methods across multiple projects. Masshunter open-access interface and automatic vial disposal provides simplified and optimised sample submission. iQ mass detector allows for process optimisation
Agilent 1290 UPLC-QTOF
Agilent
Equipped with MS/MS capability, with a high-resolution TOF stage with, ability to analyse larger molecular weight compounds such as oligonucleotides
Equipped with MS/MS capability, with a high-resolution TOF stage with, ability to analyse larger molecular weight compounds such as oligonucleotides
Agilent 6550LC/Q-TQF MS
Agilent
High Resolution Accurate Mass MS/MS instrument for Compound ID, analysis of large molecules (Oligos, Peptides, etc), trace analysis (GI’s and Nitrosamines) and complex mixture analysis
High Resolution Accurate Mass MS/MS instrument for Compound ID, analysis of large molecules (Oligos, Peptides, etc), trace analysis (GI’s and Nitrosamines) and complex mixture analysis
Agilent 6550 iFunnel Q-Tof LC/MS
Agilent
High Resolution Accurate Mass MS/MS instrument for Compound ID, analysis of large molecules (Oligos, Peptides, etc), trace analysis (GI’s and Nitrosamines) and complex mixture analysis
High Resolution Accurate Mass MS/MS instrument for Compound ID, analysis of large molecules (Oligos, Peptides, etc), trace analysis (GI’s and Nitrosamines) and complex mixture analysis
Agilent 6890N GC-FID
Agilent
Equipped with dual Flame Ionisation Detector (FID), headspace sample injector
Equipped with dual Flame Ionisation Detector (FID), headspace sample injector
Agilent 7890B GC-FID
Agilent
Equipped with dual Flame Ionisation Detector (FID) and dual injector
Equipped with dual Flame Ionisation Detector (FID) and dual injector
Agilent 8890 GC-FID-MS
Agilent
Equipped with a single-quadropole MS for impurity identification
Equipped with a single-quadropole MS for impurity identification
Agilent 8890 FID-VUV
Agilent/VUV
Equipped with Flame ionisation Detector and Vacuum UV detector to allow analysis of trace levels including moisture, and solvents in a single analytical method
Equipped with Flame ionisation Detector and Vacuum UV detector to allow analysis of trace levels including moisture, and solvents in a single analytical method
Fusion
S-Matrix
AI method development
AI method development
ICP-MS
Shimadzu
Residual metals analysis and ICHQ3D
Residual metals analysis and ICHQ3D
JEOL 400MHz NMR
Jeol
Equipped with 30 place autosampler – Used for in-house process development, confirmation of structure and assay
Equipped with 30 place autosampler – Used for in-house process development, confirmation of structure and assay
Labsolutions
Shimadzu
Used for GMP chromatography data system
Used for GMP chromatography data system
Labware
Labware
Used for GMP LIMS/ELN
Used for GMP LIMS/ELN
Metrohm Coulometric KF and Thermoprep oven
Metrohm
Water determination by KF (samples unamenable to direct KF titration)
Water determination by KF (samples unamenable to direct KF titration)
Metrohm KF Ti-Touch and Metrohm KF Titrino
Metrohm
Water determination by KF
Water determination by KF
Powder weighing cabinet x 2
SafetechSafety weighing enclosure for solids/liquids, to protect up to OEB4 (1-10ug/m3), containing 6 figure analytical balance
Shimadzu LC20/30 HPLC
Shimadzu
Equipped with 6 way column switcher for rapid reverse-phase chiral screening system
Equipped with 6 way column switcher for rapid reverse-phase chiral screening system
Shimadzu i-series 2050 x 2
Shimadzu
Used for routine sample analysis (integrated with LabSolutions DCS)
Used for routine sample analysis (integrated with LabSolutions DCS)
Shimadzu GC-MS 2020NX
Shimadzu
Also has FID detector. Impurity identification (integrated with LabSolutions DCS)
Also has FID detector. Impurity identification (integrated with LabSolutions DCS)
Shimadzu GC OAC6000
Shimadzu
GC-FID system for routine sample analysis (integrated with LabSolutions DCS)
GC-FID system for routine sample analysis (integrated with LabSolutions DCS)
Shimadzu LC40 LC-MS 2020
Shimadzu
Impurity identification (integrated with LabSolutions DCS)
Impurity identification (integrated with LabSolutions DCS)
Shimadzu Tm-UV
Shimadzu
UV instrument with temperature modifying capability to enable analysis of oligonucleotides
UV instrument with temperature modifying capability to enable analysis of oligonucleotides
Shimadzu XS UPLC
Shimadzu
Used for rapid method screening and method optimisation
Used for rapid method screening and method optimisation
Thermal Screening Unit
HEL
For identifying thermal and pressure hazards in reaction mixes and raw material liquids and powders
For identifying thermal and pressure hazards in reaction mixes and raw material liquids and powders
Thermo Vanquish Duo UPLC-CAD-MS x 2
Thermo
Equipped with CAD and DAD and dual pumps for reverse gradient. Applied to the quantification of compounds and impurities with poor chromophores
Equipped with CAD and DAD and dual pumps for reverse gradient. Applied to the quantification of compounds and impurities with poor chromophores
Waters ACQUITY H-Class UPLC-MS
Waters
Equipped with QDa mass detector, 4 column switcher with open access software
Equipped with QDa mass detector, 4 column switcher with open access software
Waters ACQUITY I-Class UPLC-MS
Waters
Equipped with Triple Quadrupole Detector (TQD) and 4 column manager, used for rapid method screening, with open access software
Equipped with Triple Quadrupole Detector (TQD) and 4 column manager, used for rapid method screening, with open access software
Crystallisation, Solid State and Preformulation
Blaze 900 probe
Blaze
Used for in-process particle characterisation by imaging and chord length distribution analysis
Used for in-process particle characterisation by imaging and chord length distribution analysis
Crystalline
Technobis
Crystallisation process design up to 8 mL with overhead stirring
Crystallisation process design up to 8 mL with overhead stirring
DSC
Mettler Toledo
Thermal and thermodynamic stability of materials with autosampler
Thermal and thermodynamic stability of materials with autosampler
DVS Intrinsic Plus
Surface Measurement Systems Ltd.
Gravimetric vapor sorption analyser used to measure the hygroscopicity of a solid
Gravimetric vapor sorption analyser used to measure the hygroscopicity of a solid
EquaVAP Evaporator
EquaVAP
Used to evaporate solvent from vials in plates
Used to evaporate solvent from vials in plates
FTIR
Shimadzu
Used to confirm the identity of a material and to differentiate between polymorphs
Used to confirm the identity of a material and to differentiate between polymorphs
Hot Stage Microscope
Leica
Assessment of crystallinity, particle shape and size, and polymorph change at varying temperatures
Assessment of crystallinity, particle shape and size, and polymorph change at varying temperatures
Lab scale fluid energy mill
FPS
Used to control the size of seed used in crystallisation studies
Used to control the size of seed used in crystallisation studies
Malvern 3000 particle sizer
Malvern Panalytical
Particle size measurements
Particle size measurements
microDISS Profiler
Pion
Used to measure the dissolution profiles of API in physilogic media
Used to measure the dissolution profiles of API in physilogic media
Microscope
Zeiss
High resolution assessment of crystallinity, particle shape and size
High resolution assessment of crystallinity, particle shape and size
Mya 4 Reaction Station
Radley
A 4-zone reaction station offering safe and precise heating, active cooling, software control and data-logging for 24/7 unattended chemistry
A 4-zone reaction station offering safe and precise heating, active cooling, software control and data-logging for 24/7 unattended chemistry
Parallel Crystalliser – Crystal 16
Technobis
Used to build solubility curves. 16 parallel screens in volumes 0.5 – 1.5 mL
Used to build solubility curves. 16 parallel screens in volumes 0.5 – 1.5 mL
Radley Reactor-Ready
Radley
Universal reactor work station with a range of easily interchangeable vessels from 250 mL to 5 L which can be configured to suit the chemistry and scale needed for each project
Universal reactor work station with a range of easily interchangeable vessels from 250 mL to 5 L which can be configured to suit the chemistry and scale needed for each project
Stability chambers
Camlab
Investigational stability of drug substance and drug product
Investigational stability of drug substance and drug product
Stability oven
Memmert
Used to evaluate the stability of API over time under controlled temperature, humidity and light environments
Used to evaluate the stability of API over time under controlled temperature, humidity and light environments
Tapped bulk density
Anton-Paar
Used to assess flowability of powders handled
Used to assess flowability of powders handled
TGA
Mettler Toledo
Levels of loosely bound solvent
Levels of loosely bound solvent
VacMaster Filtration Unit
Biotage
Used to assess filtrations before scale-up
Used to assess filtrations before scale-up
XRPD
Malvern Panalytical
Identification of solid state forms
Identification of solid state forms
Oligonucleotides PR&D
Agilent 1260 preparative system
Agilent
Preparative HPLC for rapid purification of oligonucleotide using reverse phase, HILIC, anion exchange or SEC methods
Preparative HPLC for rapid purification of oligonucleotide using reverse phase, HILIC, anion exchange or SEC methods
Agilent LC-MSD
Agilent
High throughput LC mass spec for identification and purification by mass detection
High throughput LC mass spec for identification and purification by mass detection
Agilent qToF LCMS
Agilent
High resolution mass spec for quantitative analysis and MS-MS sequencing
High resolution mass spec for quantitative analysis and MS-MS sequencing
ÄKTA Flux
Cytiva
Membrane filtration and salt exchange
Membrane filtration and salt exchange
ÄKTA oligosynt™
Cytiva
50 mg to 10 g supply of high purity oligonucleotide for toxicology, in vivo or similar experiments
50 mg to 10 g supply of high purity oligonucleotide for toxicology, in vivo or similar experiments
ÄKTA OligoSynt™
Cytiva
10 µmol to 12 mmol synthesis scale. Compact, fully automated oligonucleotide synthesizer with broad scale for robust and scalable process development and transfer to manufacturing
10 µmol to 12 mmol synthesis scale. Compact, fully automated oligonucleotide synthesizer with broad scale for robust and scalable process development and transfer to manufacturing
MerMade 12 Oligonucleotide Synthesiser
LGC
50 nmol to 20 µmol synthesis scale. Medium throughput synthesiser with a 12-column configuration and 20 amidite positions
50 nmol to 20 µmol synthesis scale. Medium throughput synthesiser with a 12-column configuration and 20 amidite positions
MerMade 192X
LGC
Synthesis of 192 oligonucleotides in parallel from 1 nmol to 1 µmol synthesis scale.
Synthesis of 192 oligonucleotides in parallel from 1 nmol to 1 µmol synthesis scale.
Waveprep
Milestone
High pressure vapour deprotection for fast and effective oligonucleotide processing
High pressure vapour deprotection for fast and effective oligonucleotide processing
Oligonucleotides Analytical
Agilent 1290 Infinity II Prep-LC
Agilent
Agilent 1290 Infinity II UPLC
Agilent
Agilent AdvanceBio 6545XT QToF w/ BioConfirm
Agilent
ThermoFisher NanoDrop One-C
ThermoFisher
Prep Chromatography
ABSys Prep SFC
ABSys
Converted HPLC System with Valve collection (for large scale projects)
Converted HPLC System with Valve collection (for large scale projects)
ABSys Prep SFC
ABSys
Prep SFC System with Valve collection (for large scale projects)
Prep SFC System with Valve collection (for large scale projects)
Agilent 1290 Prep LCMS
Agilent
Mass Direct Gradient Prep System with Open Bed PC
Mass Direct Gradient Prep System with Open Bed PC
Berger Multigram II
Berger
Prep SFC System with Valve collection
Prep SFC System with Valve collection
Gilson Prep HPLC
Gilson Gradient System with Valve Collection
Gilson Prep HPLC
Gilson Gradient System with Valve Collection
Gilson Prep HPLC
Gilson
Isocratic System for chiral projects
Isocratic System for chiral projects
Gilson Prep HPLC
Gilson
Isocratic System for chiral projects
Isocratic System for chiral projects
Gilson Prep HPLC with FC
Gilson
Gradient System with Open Bed FC
Gradient System with Open Bed FC
Gilson Prep HPLC with FC
Gilson
Gradient System with Open Bed FC
Gradient System with Open Bed FC
Sepiatec Prep100
Sepiatec
For small scale chiral projects
For small scale chiral projects
Sepiatec Prep100
Sepiatec
For small scale chiral projects
For small scale chiral projects
Sepiatec Prep100
Sepiatec
For small scale chiral projects
For small scale chiral projects
Teledyne AccquPrep SFC
Teledyne
Prep SFC System with Open Bed FC and valve collection
Prep SFC System with Open Bed FC and valve collection
Find Out More
Speak directly with our scientists to see how our equipment can help support your programme.