Route Selection
Synthetic Route Selection for Smarter and Sustainable Routes
We design and evaluate synthetic routes that balance cost, chance of technical success, sustainability, and manufacturability, giving you confidence that your molecule is on the right path from the start.
- Overview
- A smarter way to select your route
- What you can achieve
- Sustainable route development
- FAQs
Choosing the wrong route early on wastes time, money, and resources. Poor routes can collapse at scale and can stall even the most promising programmes. Our industry-leading route scouting removes this risk and eliminates guesswork.
By combining retrosynthetic planning, chance of technical success, parallel route scouting, and cost/PMI modelling, we identify scalable, sustainable routes that work in the real world, not just on paper. With input from our analytical, catalysis, and solid-state experts from the outset, your project moves forward with fewer surprises and greater confidence.
What You Can Achieve
Sustainable Route Selection
Sustainability is built into our route scouting workflows.
- PMI and carbon metrics – Benchmark each pathway for efficiency and impact
- Greener reagents and solvents – Bio-based, low-toxicity choices preferred from the outset
- Catalysis-first strategies – Enabling chemistry to cut steps and energy use
- Waste reduction – Fewer work-ups, solvent swaps, and inefficient intermediates
- Aligned to ESG – Metrics mapped to ICH sustainability guidance and investor reporting
We ensure that the route you take is not only the most efficient, but also the most sustainable.
Frequently Asked Questions
Synthetic route selection is the process of designing and evaluating the most efficient pathway to produce a target molecule. At CatSci, this means identifying scalable, cost-effective, and sustainable routes that balance yield, purity, and manufacturability. Our scientists combine retrosynthetic planning, experimental screening, and analytical integration to select the best path from discovery to commercial scale.
CatSci optimises synthetic routes through data-driven design, parallel route screening, and lifecycle PMI modelling. We evaluate yield, impurity control, cost, and environmental metrics to ensure each route is practical and sustainable. Our integrated teams in catalysis, analytical science, and solid-state chemistry help de-risk scale-up and deliver greener, more efficient processes.
Effective synthetic route selection ensures that a drug’s manufacturing process is safe, reliable, and commercially viable. By establishing robust, reproducible chemistry early, developers can reduce costs, minimise waste, and avoid scale-up failures. CatSci’s approach provides confidence that each route is scientifically sound, regulatory-ready, and aligned with sustainability goals.