Purification and Separation Science
Excellence in Separation Science
We deliver high-quality, efficient chromatographic solutions that accelerate discovery and optimise development by providing high purity material at every step of your process.
Our purification capabilities span small molecules, oligonucleotides, peptides, and complex synthetics from milligrams to kilograms.
- Overview
- Our separation science capabilities
- What you can achieve
- In our own words
- FAQs
Purification is often the make-or-break stage in development. As molecules grow more complex – from highly potent APIs to oligonucleotides, peptides, and hybrid constructs – achieving the required purity, recovery, and throughput demands advanced separation science and a deep understanding of both chemistry and process.
At CatSci, we combine state-of-the-art technology with scientific insight to solve even the toughest purification challenges across all modalities. Our integrated chromatography offering supports every stage of development, from discovery screening to GMP-ready purification, providing consistent quality, data integrity, and speed.
Our purification capabilities build on the expertise gained through our acquisition of Reach Separations in 2024, now fully integrated within CatSci’s end-to-end platform.
What You Can Achieve
Frequently Asked Questions
CatSci offers end-to-end purification and separation science services across small molecules, oligonucleotides, peptides, and hybrid modalities. Our expertise spans analytical and preparative chromatography (HPLC, SFC), impurity isolation, method development, and GMP-aligned validation — ensuring purity, scalability, and data integrity from discovery to manufacturing.
Absolutely. We are fortunate to work alongside some excellent peptide and oligo chemists and have designed workflows specifically for the purification of these modalities. We utilise traditional reverse phase techniques, ion pairing and even SFC to deliver pure material efficiently and sustainably.
It’s all about speed and milestones. Yes, in an ideal world you wouldn’t choose to take chromatography into development. But, asymmetric routes take time to design. We can help supply single enantiomer whilst your route is finalised, keeping your project on track, without delay.
Yes. We have an extensive analytical suite and expert analysts, allowing us to offer method development and analysis to support your development projects. For example, example monitoring and chiral integrity checks. And for those still working in discovery, we can offer library QC, ChromLogD and EPSA as part of our platform.