Process Development

Process Development for Precision, Control, and Manufacturing Readiness

We transform laboratory scale chemistry into robust, reproducible, and successful processes for material supply, delivering data-driven solutions that ensure your process performs from discovery through manufacture. 

Process Development
Quick filter:

Moving from laboratory success to reliable, large-scale manufacture is one of the most critical transitions in drug development. Yield variability, impurity control, and process robustness can all derail timelines and costs.  

At CatSci, we combine scientific rigour with practical execution to design processes that perform in the real world. Our multi-disciplinary teams work at the intersection of chemistry, analytics, and engineering to optimise every step, ensuring efficiency, safety, and sustainability.  

Process Development and Scale-Up
Route Evaluation
We assess route feasibility, risk, and cost to identify the most efficient and scalable pathway for your molecule.
Statistical-Led Optimisation
Using Design of Experiments, Bayesian optimisation, or traditional methods, we refine yield, impurity control, and efficiency to create a robust, data-driven process.
Process Robustness
Stress testing under manufacturing conditions confirms reliability and establishes a robust impurity control strategy.
Scale-up and Material Supply
Our pilot-scale facilities deliver reproducible non-GMP material from milligrams to multi-gram quantities.
Regulatory Readiness
Regulatory-aligned documentation ensures seamless tech transfer and complete confidence for your next phase.
Process development is not just about scaling up; it’s about building quality, reliability, and regulatory confidence into your processes from the start.

What You Can Achieve

Predictable Performance
Consistent yield and purity across scales 
Higher Efficiency
Reduced waste, cycle times, and cost
Built-In Quality
Robustness and control strategies developed from day one
Regulatory Confidence
Phase-appropriate documentation for seamless transfer
Accelerated Timelines
Smart experimentation and parallel workflows to meet milestones

Frequently Asked Questions

What is pharmaceutical process development?

Pharmaceutical process development is the design and optimisation of chemical processes to reliably manufacture a drug substance or product at scale. At CatSci, we develop robust, efficient, and sustainable processes that ensure consistent yield, purity, and safety from discovery through to GMP manufacture. Our approach integrates chemistry, analytics, and engineering for full lifecycle control. 

How does CatSci ensure scalability in process development?

CatSci ensures scalability through data-driven experimental design, pilot-scale testing, and cross-functional collaboration. Using statistical-led optimisation (Design of Experiments, Bayesian optimisation, or traditional methods), we optimise reaction conditions, impurity control, and process robustness. Each step is stress-tested under manufacturing conditions to deliver reliable, reproducible performance across scales. 

Does CatSci provide regulatory-ready process documentation?

Yes. CatSci delivers ICH Q14-aligned documentation and complete tech-transfer packages for every project. Our pharmaceutical process development services include validated analytical data, impurity lifecycle mapping, and transparent decision records — ensuring smooth partner handovers and regulatory confidence. 

Book a Consultation

Speak directly with our scientists about your development challenges and explore how we can support your programme.