GMP Drug Substance

Integrated GMP Transition – Smooth, Compliant, and Completely Managed By Us

We take your molecule from development to GMP manufacture through a fully integrated model. You work with one team — CatSci — while we coordinate every technical, analytical, and operational detail with our trusted GMP partners.

GMP Drug Substance Manufacturing
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The Importance of GMP Substance Manufacture

Transitioning into GMP manufacture is a critical milestone. It’s one that depends on robust process design, validated analytics, and precise documentation. Gaps or inconsistencies at this stage can lead to costly delays or regulatory setbacks. 

At CatSci, we prepare your process for success before it ever enters the plant and manage the journey so you don’t have to. Our experts deliver phase-appropriate CMC data, validated analytical methods, and complete technology transfer packages. We then work directly with our trusted GMP partners, including AGC Pharma Chemicals Europe, to oversee the scale-up, technology transfer, and manufacturing integration. 

You remain in partnership with one accountable team — CatSci — while we handle every detail behind the scenes, ensuring your process performs exactly as designed, under GMP conditions. 

How We Deliver a Seamless GMP Transition
Process Readiness
We confirm that every route, parameter, and control strategy is robust, scalable, and compliant — mitigating risk before the transfer begins.
Analytical & Documentation Packages
Our regulatory-aligned analytical methods and CMC documentation are prepared, validated, and delivered as partner-ready data packs.
Tech Transfer & Partner Integration
We coordinate every element of the transfer, working with our trusted GMP partners to ensure data integrity, technical clarity, and minimal disruption.
Manufacturing Oversight
Our scientists stay engaged post-transfer, offering ongoing support, troubleshooting, and comparability studies to maintain consistency and quality.
Regulatory Assurance
We provide validated data, clear governance, and traceable communication, ensuring confidence with regulators and manufacturing partners alike.
Moving into GMP manufacturing shouldn’t mean handing over control. Our integrated approach ensures you retain scientific oversight and full confidence in every decision

What You Can Achieve

Seamless Handover
Integrated transfer management delivers a GMP-ready process with zero disruption to timelines.
Regulatory Confidence
Regulatory-compliant documentation, validated data, and transparent communication give regulators and partners full assurance.
End-to-End Continuity
We maintain technical oversight and data integrity from the bench to the plant.
Reduced Delays
Proactive coordination and validation to avoid transfer setbacks.
Assured Quality
Analytical, process, and operational consistency built and maintained through scale-up.
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Our Capabilities

From route design to regulatory submission, we solve complex problems and sustain quality at every stage.
Benefits to Your Programme
One Team, Complete Control
You work directly with CatSci; we manage the GMP interface, partners, and operations for you.
Regulatory Confidence
Documentation and validation aligned to global standards, ensuring confidence with regulators and auditors.
Integrated Partnership Network
Established partnerships with global GMP CDMOs for small molecules, peptides, oligonucleotides, and HPAPIs.
Frictionless Transfer
Coordinated logistics and validated data packages eliminate delays and minimise hand-offs.
Assured Progression
Proven processes move smoothly into GMP manufacture with maintained quality, compliance, and reproducibility.

Our Trusted Partners 

Your GMP manufacturing journey benefits from CatSci’s network of carefully selected and audited partners. Our long-standing relationships means you have peace-of-mind in your move into GMP, offering global capability with CatSci as your single point of contact. 

We collaborate with leading CDMOs and manufacturing sites, all aligned to CatSci’s stringent standards of quality, safety, and transparency. 

Together, we provide an integrated solution that feels in-house: seamless tech transfer, continuous oversight, and a unified scientific vision from development to GMP production. 

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image of translational bioscience scientist working at a glovebox
Our role is to make GMP feel seamless. You only need one team — CatSci. We coordinate every detail with our partners so that your process performs exactly as designed, with complete confidence from development to manufacture.
Ross Burn
Co-Founder & CEO
image of translational bioscience scientist working at a glovebox
At CatSci, we make external manufacturing feel internal. Our integrated approach bridges development and GMP so completely that you experience one unified workflow. It's controlled, compliant, and completely managed.
Rob Crook
Technical Director, Chemical Science

Frequently Asked Questions

What Is GMP Drug Substance Manufacturing?

GMP drug substance manufacturing is the controlled, compliant production of the active ingredient in a medicine under regulatory standards. It ensures every batch meets strict quality, safety, and data integrity requirements for use in clinical and commercial products. CatSci delivers full GMP readiness through validated processes and managed tech transfer to trusted GMP partners.

How Does CatSci Support GMP Transition?

CatSci manages every step of the transition from process development to GMP manufacturing. We ensure routes, control strategies, and analytical methods are validated, then coordinate directly with our GMP partners to transfer the process seamlessly, whilst maintaining full scientific oversight and traceability throughout.

Who Are CatSci’s GMP Manufacturing Partners?

CatSci collaborates with a network of trusted GMP CDMOs, including AGC Pharma Chemicals Europe. All partners are audited and aligned with CatSci’s standards for quality, transparency, and regulatory compliance, ensuring a unified, end-to-end GMP solution.

What Are the Benefits of CatSci’s Integrated GMP Model?

CatSci’s single-partner model eliminates hand-off risks and accelerates progression. You work with one accountable team that manages process readiness, analytical validation, and GMP coordination. We ensure control, continuity, and compliance from bench to plant.

Book a Consultation

Speak directly with our scientists about your development challenges and explore how we can support your programme.