Catalysis & Enabling Chemistry

Catalysis & Enabling Chemistry Platforms for Complex Transformations

We help overcome synthetic challenges using advanced catalytic strategies. From chemocatalysis, biocatalysis and hydrogenation, we improve efficiency, selectivity, and scalability while reducing cost and environmental impact. 

Catalysis & Enabling Chemistry
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Challenging steps can derail even the most promising synthetic pathway. Low yields, complex purifications, or unsustainable conditions waste time and resources.  

Our catalysis and enabling chemistry platforms replace those barriers with robust, elegant solutions, improving selectivity, streamlining development, and supporting long-term manufacturability.  

With expertise spanning chemocatalysis, biocatalysis, asymmetric hydrogenation, photocatalysis, and carbonylations, our scientists design catalytic strategies that simplify complexity and create lasting value for your molecule.  

Catalysis: Smarter, Sustainable Development
Route Scouting
Identify new, greener routes with unbiased catalyst and ligand screening, supported by an extensive library of ligands and high-throughput workflows.
Process Optimisation
Refine conditions with statistical design of experiments, advanced data visualisation, and mechanistic insight to deliver reproducible, scalable reactions.
Scale-Up
Move seamlessly from bench to pilot with proven reaction systems and continuous-flow compatibility, ensuring safety and efficiency at every stage.
Regulatory Enablement
Phase-appropriate data packages, including impurity mapping, kinetic understanding, and metal removal strategies, safeguard your submissions and de-risk tech transfer.
A single catalytic breakthrough can unlock multiple downstream efficiencies.

What You Can Achieve

Shorter cycle times
Rapid optimisation for faster decision making
Smarter process selection
Robust catalytic data drives clear priorities
Regulatory readiness
Avoid CMC delays with high quality processes
Smoother transitions
Processes designed with scale-up in mind
Commercial scalability
Catalytic routes proven to work at commercial scale
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Our Capabilities

From route design to regulatory submission, we solve complex problems and sustain quality at every stage.

Green Catalysis in Drug Development

Sustainability is embedded in our catalytic approach from the very first screen.

 

  • Lifecycle assessment: PMI and carbon footprint tracked throughout development
  • Greener solvents & reagents: Preference for bio-based, low-toxicity materials
  • Catalytic efficiency: Chemo- and biocatalysis platforms cut energy use and shorten routes
  • Waste minimisation: In-line monitoring and optimised work-ups reduce solvent swaps and material use
  • Regulatory alignment: Metrics mapped to ICH sustainability guidance and ESG reporting

 

We deliver catalytic solutions that are not only robust and scalable, but also auditable and environmentally responsible.

Frequently Asked Questions

What catalysis development services does CatSci offer?

CatSci provides end-to-end catalysis development services covering chemocatalysis, biocatalysis, asymmetric hydrogenation, and CO-based transformations. Our experts design, optimise, and scale catalytic routes that enhance selectivity, efficiency, and sustainability from discovery through to GMP manufacturing. 

Does CatSci support biocatalysis and asymmetric catalysis?

Yes. CatSci’s catalytic platforms include enzyme sourcing, cofactor screening, and asymmetric hydrogenation, enabling greener, more selective reactions. We use high-throughput workflows and design of experiments (DoE) to deliver robust, scalable catalytic solutions across diverse molecular classes. 

How does CatSci make catalysis more sustainable?

Sustainability is embedded in every CatSci catalytic project. We apply lifecycle PMI assessment, solvent and reagent optimisation, and bio-based materials to minimise waste and energy use. Our catalytic processes align with ICH and ESG standards, ensuring greener, auditable, and high-performance chemistry. 

Book a Consultation

Speak directly with our scientists about your development challenges and explore how we can support your programme.