• Knowledge Hub
  • News & Events
  • Careers
  • Contact Us
CatSci Logo

  • Home
  • Who we are
  • What we do
    • Early Development
    • Late Development
  • Digital Walkthrough
☰
  • Home
  • Who we are
  • What we do
    • Early Development
    • Late Development
  • Digital Walkthrough

  • Knowledge Hub
  • News & Events
  • Careers
  • Contact Us
We're hiring!

Early Development

Providing perfect-for-purpose solutions, tailored to the evolving needs of pre-clinical & Phase I projects.

Jo Sampson

Route Scouting and Selection

CatSci is committed to finding the most sustainable routes for your project, which starts with route scouting and selection. Discover how our expertise can help you increase efficiency and reduce waste of your reactions and processes. Check out our case study on effective route scouting here.

Route Scouting and Selection

CatSci is committed to finding the most sustainable routes for your project, which starts with route scouting and selection. Discover how our expertise can help you increase efficiency and reduce waste of your reactions and processes.

  • Route invention
  • Route design and assessment
  • Reaction understanding
  • Route familiarisation
  • Proof of principle
  • Demonstration batches

We work efficiently and effectively with you to scale up your processes from milligrams to kilos. Our early scale-up solutions ensure the safety, proficiency and economic sustainability of your processes from the start.

Early Scale-up

Early Scale-up

We work efficiently and effectively with you to scale up your processes from milligrams to kilos. Our early scale-up solutions ensure the safety, proficiency and economic sustainability of your processes from the start.

  • Rapid development and scale-up
  • Critical process development
  • Thermal hazards / process safety
  • Non-GMP material supply (incl. OEB-4)
  • Tech transfer for GMP manufacture
CatSci scientist

Risk Management

CatSci can safely manage the full complexity of your process research and development projects. We have the capabilities to help de-risk your pharmaceutical pipeline of small molecule assets, by safely and securely delivering all your project demands.

Risk Management

CatSci can safely manage the full complexity of your process research and development projects. We have the capabilities to help de-risk your pharmaceutical pipeline of small molecule assets, by safely and securely delivering all your project demands.

  • Process robustness
  • Quality targets
  • Design space exploration / modelling

Our project leads work with you to understand your specific goals to ensure tailored analytical methodology. We have a 3:1 chemist-to-analyst ratio and 100 years of combined experience of analytical problem solving. ​Check out our case study on Method development for high-throughput sample analysis here.

Analytical Excellence

Analytical Excellence

Our project leads work with you to understand your specific goals to ensure tailored analytical methodology. We have a 3:1 chemist-to-analyst ratio and 100 years combined experience of analytical problem solving. ​

  • High throughput reaction profiling​
  • Method development (in-silico, screening and optimisation)​
  • Impurity identification and characterisation (including on-site NMR)​
  • Analytical method qualification aligned with ICHQ2​
  • Solid state analysis for salt / polymorph screening
CatSci scientist

Enabling Science

We possess a range of enabling technologies in multiple areas including catalysis and material science, which provide us with the right tools to bring you access to the best chemistry. By utilising state-of-the-art technology, we help you to create small molecule therapeutics in a safer, greener and more cost-effective way. Check out our blog on the physical chemistry of salt screening or our case study on designing a robust catalytic process.

Enabling Science

Catalysis

  • State-of-the-art expertise in homogeneous & heterogeneous catalysis, inc. asymmetric hydrogenation
  • Reaction screening & catalyst selection, inc. high pressure reactions & biocatalysis
  • Medium-throughput & data-rich experimental workflows
  • Extensive library of 500 ligands
  • New route exploration and unbiased approach to catalyst and ligand screening
  • Trouble-shooting
  • Manufacturability
  • Metal control / removal

Material Science

  • Solid state version definition
  • Polymorph screening and control
  • Solubility screen
  • Crystallisation process definition
  • Filtration washing and drying
  • Crystallisation scalability risk assessment
  • Control strategy definition
  • Formulation manufacturability

Late Development

Learn more about our Late Development services.

CatSci fume hoods

Knowledge Hub

Check out our case studies, postcards and more in the Knowledge Hub.

CatSci scientists fume hood

Contact us

Get in touch to find out more or discuss your project objectives.

  • Home
  • Who we are
  • What we do
    • Early Development
    • Late Development
  • Digital Walkthrough
  • Knowledge Hub
  • News & Events
  • Careers
  • Contact Us

Stay in Touch

Sign up
  • Safety, Health & Environment
  • Privacy Policy

© 2011-2021 CatSci Ltd. All rights reserved.
Registered in England & Wales.
Company No. 07466141.

Cookies

This site uses cookies: Find out more.